![]() ![]() Routes vary in the onset, bioavailability and duration of active effects for each person. Ketamine can be administered in a variety of ways, including as an intravenous infusion (IV), intramuscular injection (IM), intranasally, or sublingually/orally as a dissolving troche or tablet. Because of this, it is not necessary to stop using your SSRIs in order to benefit from ketamine. Other psychedelics and SSRIs work on the serotonin pathway. Ketamine is an NMDA antagonist and works on the glutamate neurotransmitter system. Ketamine works on a different pathway than other classic psychedelics. Your providers serve as guides, and assist in processing the experience and its impact on your everyday life. These sorts of peak experiences have been shown to expand one’s sense of self and understanding of existence, and may enable you to access your own healing wisdom. Ketamine has the potential to create a non-ordinary state of consciousness, facilitating a profound transpersonal or mystical peak experience. We offer a psychotherapy program that will prepare you for your ketamine sessions, encourage you to explore your mind while within the ketamine space, and assist you in integrating your experiences afterwards. We think the administration of ketamine may be most effective when paired with psychotherapy. Some practitioners view the psychedelic and dissociative experiences that occur at higher doses to provide a more robust and longer-lasting outcome and we concur. Though research has demonstrated an antidepressant response to low doses that are minimally psychoactive or sub-psychedelic, this effect tends to be cumulative, requiring repeated administrations over short periods of time. Most infusion centers are not doing concurrent therapy with the administration of ketamine. It is a relatively new approach that arose out of the data coming out of ketamine infusion centers who were seeing improvement in mental health conditions. The therapy is done before, during, and after you ingest the ketamine. The ketamine is a tool to enhance therapy. It is considered a psychedelic assisted therapy and the focus is on the psychotherapy. KAP is basically psychotherapy with the assistance of ketamine. What is Ketamine Assisted Psychotherapy (KAP)? Ketamine has been increasingly used “off-label” to treat various chronic and treatment-resistant mental health conditions, such as depression, alcoholism, substance dependencies, post-traumatic stress disorder, anxiety disorders, and other psychiatric diagnoses. Once a medication is approved by the FDA, physicians may use it “off-label,” meaning for purposes other than what is listed on the label, as long as the use is based on sound medical evidence. When a new drug is approved for medical use, the manufacturer produces a “label” to explain its use as approved by the FDA. ![]() It has also been utilized successfully in managing acute and chronic pain conditions due to its analgesic properties. As an anesthetic, ketamine is most commonly used in surgical settings, including pediatric surgery, due to its excellent safety profile, particularly around breathing/airway management. It is one of the most widely used drugs in modern medicine, and is on the World Health Organization’s List of Essential Medicines. Ketamine is a synthetic pharmaceutical compound, classified as a dissociative anesthetic. ![]()
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